Single shot vaccine

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Johnson & Johnson's single-shot COVID vaccine approved in India

Single shot COVID Vaccine. Know more…

Tuesday, 10th August 2021

The coronavirus vaccination campaign is in full swing and millions of people have been vaccinated. In the growing number of Delta mutation cases, it has become an hour-long necessity, and vaccinations continue to put us at greater risk of infection.

As vaccine shortages remain the main challenge facing India, many international vaccines have recently been approved in India. In other words, according to Federal Minister of Health Mansuk Mandavia, Johnson & Johnson's single-dose COVID19 vaccine has received emergency use approval (USA) in India.

In a tweet, he said: “India has expanded its vaccine basket! Johnson & Johnson's single-dose COVID19 vaccine has been approved for emergency use in India. Now there are 5 USA vaccines in India. This will further promote the collective struggle in our country. "


Also Read: How COVID affects your brain health and five ways to enhance your brain health.


J & J's COVID vaccine is the fifth vaccine to receive Emergency Use Authorisation (EUA) in India

In addition to Johnson & Johnson's COVID vaccine, four vaccines have received emergency use authorization (USA) in India. Covishield from Oxford AstraZeneca, Covaxin from Bharat Biotech, Sputnik V from Russia, and Moderna from the United States.

India has reportedly received more than 500 million doses of vaccine so far and more than 4.955 million doses of vaccine have been vaccinated in the last 24 hours. Although the number is high, there are still many people who have not been vaccinated due to a shortage or doubt about the vaccine.


How does it compare with other vaccines?

As of now, Johnson & Johnson's COVID vaccine is the only single-injection vaccine available, so it is considered a game-changer. Unlike other COVID vaccines that must be injected in two doses, it is a single dose vaccine injection, which makes it very special and different from other vaccines.

An earlier clinical trial found that one dose of Johnson & Johnson's vaccine produced a strong immune response in most people. This, in turn, led to a single-dose vaccine regimen. In contrast, other US-made vaccines, such as the Pfizer and Moderna vaccines, produce a lower immune response after one dose, so a second dose appears to be necessary.


Also Read: Coronavirus: Can Eye Exams Diagnose COVID Long-Term? Here's what the research found.


What makes the single-dose vaccine so different?

Johnson & Johnson's COVID vaccine is a viral vector vaccine. The virus vector vaccine uses another virus to produce antibodies against deadly pathogens, that is, it triggers an immune response by using an improved version of a different virus (called a vector). For the coronavirus, the Johnson & Johnson team used an adenovirus, a virus from the common cold. When injected into someone’s arm, it attaches to cells, and these cells read what is needed to produce the SARsCOV2 spike protein. Genetic instructions.

After protein production reaches its peak, the immune system detects these invaders and produces antibodies. On the other hand,

Pfizer and Moderna were developed through messenger RNA (mRNA) technology. The mRNA vaccine triggers an immune response by activating cells against deadly pathogens. In the case of coronaviruses, this vaccine instructs cells to produce a coronavirus spike protein or protein segment to generate an immune response in the body. This, in turn, produced the antibodies needed to fight the deadly SARsCOV2 virus.


Is Johnson & Johnson's COVID vaccine effective?

Janssen Pharmaceuticals, the COVID vaccine division of Johnson & Johnson, received emergency use authorization in the United States in February last year.

The US Food and Drug Administration (FDA) reviewed the results of clinical trials involving more than 40,000 people and concluded that the developed vaccine can provide protection against mild to moderate and severe to critical COVID cases19. It was found to have 72 effects in preventing all forms of SARsCOV2 virus and 86 effects in preventing severe cases.

Although people who have received the Johnson & Johnson COVID vaccine may still be infected with the disease, they are unlikely to develop a serious infection and require hospitalization.


Also Read: Research states patients with mental health issues are more prone to covid related complications and mortality.


How long will the protection from the vaccine last?

Although the COVID vaccine is said to be effective, there is no conclusive evidence to show how long the vaccine can protect us from the virus.

However, previous clinical trials have shown that a single dose of the vaccine produces a strong immune response in most people. The report showed that even 71 days after vaccination, antibody levels remained stable and increased.

Although the Johnson & Johnson vaccine has proven effective so far, it may need to be boosted in the future.


The News Talkie Bureau


Timesofindia Indiatimes

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